While avoiding common retinoid side effects.

RetileX-A® provides powerful retinoid therapy and eliminates side effects such as redness and itching, by using a unique nano-encapsulation technology that ensures retinoid molecules are transported deeper into the skin – where they are needed most.

Combine Nourella® cream with Nourella® tablets with Vercilex® for a dual action therapy that delivers clinically proven, age reversing effects.

Each retinoid molecule in Nourella® cream is surrounded by nano-encapsulation technology


Retilex-A®: The next-generation retinoid

The proprietary technology RetileX-A® creates an ‘envelope’ around each retinoid molecule in Nourella® cream, protecting molecules from light and oxidation and carrying them past the epidermis directly to the skin’s keratinocytes – where molecules are then released and can exert their full efficacy.

RetileX-A® was developed by Pharma Medico in Scandinavia as a next-generation retinoid and is backed by more than 30 years of research.

Nourella® Cream with Retilex-A® improves the structure and appearance of aged skin by:

  • Normalising the thickness and texture of the epidermis
  • Preventing the degradation of collagen and elastin
  • Stimulating the synthesis of collagen and elastin
  • Promoting angiogenesis and dermal blood perfusion
  • Providing antioxidant and anti-inflammatory activities
  • Depigmenting and inhibiting melanin synthesis

Development of Retilex-A® has focused on:

  • Improving the overall absorbed dosage of retinyl palmitate by molecular stabilisation and reducing degradation
  • Optimising transdermal delivery and diffusion of the active compound (300x increase compared to conventional retinoids)
  • Extending the drug release and time available by its unique buffering effect
  • Preventing drug–drug and drug–excipient interactions by providing physical and chemical protection
  • Minimising adverse effects by restricting the contact time between the free retinoid and the skin surface
  • Enhancing the stability and shelf life of Nourella® cream